Buprenorphine is the main active ingredient contained in Subutex and Suboxone (Suboxone also contains naloxone) and, in higher doses, is used to treat opioid dependence. At lower doses, it is commonly used to treat moderate chronic pain. Buprenorphine is a derivative of the opium poppy plant like other drugs, such as morphine and heroin are; However, it is not quite as strong as these drugs. This is because the buprenorphine is a partial opioid agonist drugs such as morphine, heroin and oxycontin are complete opioid agonists.
Basically, this means, is that when an individual is given buprenorphine, the chemical partially active in the individual brain opioid receptors, causing the person to feel slightly euphoric, but well short of the intensity that they feel if they were to take a full agonist opioid such as heroin.
When a person drinks the heroin (a number any methods), the drug fully active a opioids in the brain receptors, causing a feeling high through the central nervous system of the body (assuming that the dose is high enough). Obviously, quite small doses, will be felt without effect. This is why mental and physical dependence is so common with opiates because the body learns to love the feeling and finally very difficult to cope without it.
Potential adverse effects of buprenorphine
Like other opiates, buprenorphine can also cause minor to serious side effects. More serious side effects, however, are more common in people who do not already have tolerance built into their body for opioids (non-opiate addicts). It is people who can be introduced to the drug for the first time and eventually take too, which can lead to breathing difficulties, nausea and even death by respiratory failure (rare). However, buprenorphine taken from people who already have a tolerance to opioids are much less likely to experience more serious consequences as the overdose and death, however, side effects such as nausea, constipation, irregular breathing, slow heartbeat, sexual frustration, urinary retention (difficulty urinating), the insomnia and dryness of the mouth are extremely common.
When starting the buprenorphine as the Suboxone treatment, it is important that the individual has not taken any other opiates for 12 to 18 hours at least before the first dose of buprenorphine, otherwise they could be placed in precipitated withdrawal essentially characterized by the intensification of the withdrawal symptoms (worse than the withdrawals to the opiate normal that the person is used to). To avoid withdrawal symptoms precipitated, follow the orders of doctors and make sure that you are currently in withdrawal at the time of your first buprenorphine administered (or Suboxone) dose.
As with many other drugs, buprenorphine can cause serious (and potentially fatal) side effects if the drug is combined with other drugs (especially the antidepressants or tranquilizers). Current medications associated with negative consequences include xanax, valium, alcohol, heroin, vicodin, oxycontin and methadone. When these drugs are combined with buprenorphine, they amplify the effect of sedetary on the respiratory system and can lead to respiratory or failure (which is the most common cause of death) heart. How do the buprenorphine (such as Suboxone)?
The most common form of buprenorphine for the treatment of opioid dependence is Suboxone contains four parts buprenorphine for each naloxone part. Naloxone counters the effect of buprenorphine to reduce the risk of abuse Suboxone occur. There are two options for taking Suboxone; Film of Suboxone and Suboxone pills. The Film sublingual Suboxone is a more recent version of the manufacturer and is more convenient for most people, because it is easy to cut the pieces to match the dose you need and taste is less intense. The sublingual pill or Tablet is a soft tablet which generally divides crumble when you try to reduce parts (I would not recommend the use of this option). With the other option, you take the piece of the band or the pill and put it under your tongue to dissolve. You do not want chewing or swallowing drugs as this would cancel the intended effects of the drug.
Jason Mears is a blogger, musician, business owner, former opiate addict and founder of suboxoneinformation.org which is a web portal non-profit dedicated to inform people on Suboxone and its effectiveness in treating opioid dependence. To learn more about the buprenorphine and Suboxone and how it can help you or the person you care defeat their opioid dependence, visit http://www.suboxoneinformation.org/.
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